Simultaneous Quantification and Pharmacokinetic Characterization of Doxapram and 2-Ketodoxapram in Porcine Plasma and Brain Tissue

Atrial fibrillation (AF) is an arrhythmia associated with an increased stroke risk and mortality rate. Current treatment options leave unmet needs in AF therapy. Recently, doxapram has been introduced as a possible new option for AF treatment in a porcine animal model. To better understand its pharm...

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Detalles Bibliográficos
Autores principales: Kraft, Manuel, Foerster, Kathrin I., Wiedmann, Felix, Sauter, Max, Paasche, Amelie, Blochberger, Pablo L., Yesilgöz, Baran, L’hoste, Yannick, Frey, Norbert, Haefeli, Walter E., Burhenne, Jürgen, Schmidt, Constanze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031635/
https://www.ncbi.nlm.nih.gov/pubmed/35456597
http://dx.doi.org/10.3390/pharmaceutics14040762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031635/
https://www.ncbi.nlm.nih.gov/pubmed/35456597
http://dx.doi.org/10.3390/pharmaceutics14040762

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