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TR3 Enhances AR Variant Production and Transactivation, Promoting Androgen Independence of Prostate Cancer Cells

SIMPLE SUMMARY: Advanced prostate cancer development is associated with androgen-independent AR signaling. TR3 overexpression alters AR expression, splicing process, and transactivation towards increasing the androgen independence of AR signaling in prostate cancer cells. These results suggest that...

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Detalles Bibliográficos
Autores principales: Tran, Tuyen Thanh, Lee, Keesook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031921/
https://www.ncbi.nlm.nih.gov/pubmed/35454821
http://dx.doi.org/10.3390/cancers14081911