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Cross Strain Protection against Cytomegalovirus Reduces DISC Vaccine Efficacy against CMV in the Guinea Pig Model

Congenital cytomegalovirus (CMV) is a leading cause of disease in newborns and a vaccine is a high priority. The guinea pig is the only small animal model for congenital CMV but requires guinea pig cytomegalovirus (GPCMV). Previously, a disabled infectious single cycle (DISC) vaccine strategy demons...

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Detalles Bibliográficos
Autores principales: Choi, K. Yeon, El-Hamdi, Nadia S., McGregor, Alistair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031936/
https://www.ncbi.nlm.nih.gov/pubmed/35458490
http://dx.doi.org/10.3390/v14040760