Squalene-Based Nano-Assemblies Improve the Pro-Autophagic Activity of Trehalose

The disaccharide trehalose is a well-established autophagy inducer, but its therapeutic application is severely hampered by its low potency and poor pharmacokinetic profile. Thus, we targeted the rational design and synthesis of trehalose-based small molecules and nano objects to overcome such issue...

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Detalles Bibliográficos
Autores principales: Frapporti, Giulia, Colombo, Eleonora, Ahmed, Hazem, Assoni, Giulia, Polito, Laura, Randazzo, Pietro, Arosio, Daniela, Seneci, Pierfausto, Piccoli, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032118/
https://www.ncbi.nlm.nih.gov/pubmed/35456696
http://dx.doi.org/10.3390/pharmaceutics14040862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032118/
https://www.ncbi.nlm.nih.gov/pubmed/35456696
http://dx.doi.org/10.3390/pharmaceutics14040862

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