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Squalene-Based Nano-Assemblies Improve the Pro-Autophagic Activity of Trehalose
The disaccharide trehalose is a well-established autophagy inducer, but its therapeutic application is severely hampered by its low potency and poor pharmacokinetic profile. Thus, we targeted the rational design and synthesis of trehalose-based small molecules and nano objects to overcome such issue...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032118/ https://www.ncbi.nlm.nih.gov/pubmed/35456696 http://dx.doi.org/10.3390/pharmaceutics14040862 |