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Microglial FABP4-UCP2 Axis Modulates Neuroinflammation and Cognitive Decline in Obese Mice

The microglial fatty-acid-binding protein 4-uncoupling protein 2 (FABP4-UCP2) axis is a key regulator of neuroinflammation in high-fat-diet (HFD)-fed animals, indicating a role for FABP4 in brain immune response. We hypothesized that the FABP4-UCP2 axis is involved in regulating diet-induced cogniti...

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Detalles Bibliográficos
Autores principales: So, Simon W., Fleming, Kendra M., Duffy, Cayla M., Nixon, Joshua P., Bernlohr, David A., Butterick, Tammy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032181/
https://www.ncbi.nlm.nih.gov/pubmed/35457171
http://dx.doi.org/10.3390/ijms23084354