Cargando…

Preparation of 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones via base-assisted cyclization of 3-cyanoketones

A convenient preparative method is developed allowing for expeditious assembly of 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones from routinely available inexpensive synthetic precursors. These compounds could not be prepared via the previously known protocols, as 2-aminofuran derivati...

Descripción completa

Detalles Bibliográficos
Autores principales: Aksenov, Nicolai A., Aksenov, Dmitrii A., Kurenkov, Igor A., Aksenov, Alexander V., Skomorokhov, Anton A., Prityko, Lidiya A., Rubin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032200/
https://www.ncbi.nlm.nih.gov/pubmed/35479147
http://dx.doi.org/10.1039/d1ra02279b