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Preparation of 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones via base-assisted cyclization of 3-cyanoketones

A convenient preparative method is developed allowing for expeditious assembly of 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones from routinely available inexpensive synthetic precursors. These compounds could not be prepared via the previously known protocols, as 2-aminofuran derivati...

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Detalles Bibliográficos
Autores principales:	Aksenov, Nicolai A., Aksenov, Dmitrii A., Kurenkov, Igor A., Aksenov, Alexander V., Skomorokhov, Anton A., Prityko, Lidiya A., Rubin, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032200/ https://www.ncbi.nlm.nih.gov/pubmed/35479147 http://dx.doi.org/10.1039/d1ra02279b

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