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The Development of the Davis Food Glycopedia—A Glycan Encyclopedia of Food
The molecular complexity of the carbohydrates consumed by humans has been deceptively oversimplified due to a lack of analytical methods that possess the throughput, sensitivity, and resolution required to provide quantitative structural information. However, such information is becoming an integral...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032246/ https://www.ncbi.nlm.nih.gov/pubmed/35458202 http://dx.doi.org/10.3390/nu14081639 |
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author | Castillo, Juan J. Couture, Garret Bacalzo, Nikita P. Chen, Ye Chin, Elizabeth L. Blecksmith, Sarah E. Bouzid, Yasmine Y. Vainberg, Yael Masarweh, Chad Zhou, Qingwen Smilowitz, Jennifer T. German, J. Bruce Mills, David A. Lemay, Danielle G. Lebrilla, Carlito B. |
author_facet | Castillo, Juan J. Couture, Garret Bacalzo, Nikita P. Chen, Ye Chin, Elizabeth L. Blecksmith, Sarah E. Bouzid, Yasmine Y. Vainberg, Yael Masarweh, Chad Zhou, Qingwen Smilowitz, Jennifer T. German, J. Bruce Mills, David A. Lemay, Danielle G. Lebrilla, Carlito B. |
author_sort | Castillo, Juan J. |
collection | PubMed |
description | The molecular complexity of the carbohydrates consumed by humans has been deceptively oversimplified due to a lack of analytical methods that possess the throughput, sensitivity, and resolution required to provide quantitative structural information. However, such information is becoming an integral part of understanding how specific glycan structures impact health through their interaction with the gut microbiome and host physiology. This work presents a detailed catalogue of the glycans present in complementary foods commonly consumed by toddlers during weaning and foods commonly consumed by American adults. The monosaccharide compositions of over 800 foods from diverse food groups including Fruits, Vegetables, Grain Products, Beans, Peas, Other Legumes, Nuts, Seeds; Sugars, Sweets and Beverages; Animal Products, and more were obtained and used to construct the “Davis Food Glycopedia” (DFG), an open-access database that provides quantitative structural information on the carbohydrates in food. While many foods within the same group possessed similar compositions, hierarchical clustering analysis revealed similarities between different groups as well. Such a Glycopedia can be used to formulate diets rich in specific monosaccharide residues to provide a more targeted modulation of the gut microbiome, thereby opening the door for a new class of prophylactic or therapeutic diets. |
format | Online Article Text |
id | pubmed-9032246 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90322462022-04-23 The Development of the Davis Food Glycopedia—A Glycan Encyclopedia of Food Castillo, Juan J. Couture, Garret Bacalzo, Nikita P. Chen, Ye Chin, Elizabeth L. Blecksmith, Sarah E. Bouzid, Yasmine Y. Vainberg, Yael Masarweh, Chad Zhou, Qingwen Smilowitz, Jennifer T. German, J. Bruce Mills, David A. Lemay, Danielle G. Lebrilla, Carlito B. Nutrients Article The molecular complexity of the carbohydrates consumed by humans has been deceptively oversimplified due to a lack of analytical methods that possess the throughput, sensitivity, and resolution required to provide quantitative structural information. However, such information is becoming an integral part of understanding how specific glycan structures impact health through their interaction with the gut microbiome and host physiology. This work presents a detailed catalogue of the glycans present in complementary foods commonly consumed by toddlers during weaning and foods commonly consumed by American adults. The monosaccharide compositions of over 800 foods from diverse food groups including Fruits, Vegetables, Grain Products, Beans, Peas, Other Legumes, Nuts, Seeds; Sugars, Sweets and Beverages; Animal Products, and more were obtained and used to construct the “Davis Food Glycopedia” (DFG), an open-access database that provides quantitative structural information on the carbohydrates in food. While many foods within the same group possessed similar compositions, hierarchical clustering analysis revealed similarities between different groups as well. Such a Glycopedia can be used to formulate diets rich in specific monosaccharide residues to provide a more targeted modulation of the gut microbiome, thereby opening the door for a new class of prophylactic or therapeutic diets. MDPI 2022-04-14 /pmc/articles/PMC9032246/ /pubmed/35458202 http://dx.doi.org/10.3390/nu14081639 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Castillo, Juan J. Couture, Garret Bacalzo, Nikita P. Chen, Ye Chin, Elizabeth L. Blecksmith, Sarah E. Bouzid, Yasmine Y. Vainberg, Yael Masarweh, Chad Zhou, Qingwen Smilowitz, Jennifer T. German, J. Bruce Mills, David A. Lemay, Danielle G. Lebrilla, Carlito B. The Development of the Davis Food Glycopedia—A Glycan Encyclopedia of Food |
title | The Development of the Davis Food Glycopedia—A Glycan Encyclopedia of Food |
title_full | The Development of the Davis Food Glycopedia—A Glycan Encyclopedia of Food |
title_fullStr | The Development of the Davis Food Glycopedia—A Glycan Encyclopedia of Food |
title_full_unstemmed | The Development of the Davis Food Glycopedia—A Glycan Encyclopedia of Food |
title_short | The Development of the Davis Food Glycopedia—A Glycan Encyclopedia of Food |
title_sort | development of the davis food glycopedia—a glycan encyclopedia of food |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032246/ https://www.ncbi.nlm.nih.gov/pubmed/35458202 http://dx.doi.org/10.3390/nu14081639 |
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