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Rare and Common Variants Uncover the Role of the Atria in Coarctation of the Aorta

Coarctation of the aorta (CoA) and bicuspid aortic valve (BAV) often cooccur and are genetically linked congenital heart defects (CHD). While CoA is thought to have a hemodynamic origin from ventricular dysfunction, we provide evidence pointing to atrial hemodynamics based on investigating the genet...

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Detalles Bibliográficos
Autores principales: Zhu, Wenjuan, Williams, Kylia, Young, Cullen, Lin, Jiaunn-Huey, Teekakirikul, Polakit, Lo, Cecilia W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032275/
https://www.ncbi.nlm.nih.gov/pubmed/35456442
http://dx.doi.org/10.3390/genes13040636