Ageritin—The Ribotoxin-like Protein from Poplar Mushroom (Cyclocybe aegerita) Sensitizes Primary Glioblastoma Cells to Conventional Temozolomide Chemotherapy

Here, we propose Ageritin, the prototype of the ribotoxin-like protein family, as an adjuvant treatment to control the growth of NULU and ZAR, two primary human glioblastoma cell lines, which exhibit a pharmacoresistance phenotype. Ageritin is able to inhibit NULU and ZAR growth with an IC50 of 0.53...

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Detalles Bibliográficos
Autores principales: Rotondo, Rossella, Ragucci, Sara, Castaldo, Salvatore, Landi, Nicola, Oliva, Maria Antonietta, Pedone, Paolo V., Di Maro, Antimo, Arcella, Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032345/
https://www.ncbi.nlm.nih.gov/pubmed/35458581
http://dx.doi.org/10.3390/molecules27082385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032345/
https://www.ncbi.nlm.nih.gov/pubmed/35458581
http://dx.doi.org/10.3390/molecules27082385

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