Identification of functionally important domains of human cytomegalovirus gO that act after trimer binding to receptors

Human cytomegalovirus (HCMV) entry involves trimer (gH/gL/gO) that interacts with PDGFRα in fibroblasts. Entry into epithelial and endothelial cells requires trimer, which binds unidentified receptors, and pentamer (gH/gL/UL128-131), which binds neuropilin-2. To identify functionally important domai...

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Detalles Bibliográficos
Autores principales: Chin, Andrea, Liu, Jing, Jardetzky, Theodore, Johnson, David C., Vanarsdall, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032346/
https://www.ncbi.nlm.nih.gov/pubmed/35452493
http://dx.doi.org/10.1371/journal.ppat.1010452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032346/
https://www.ncbi.nlm.nih.gov/pubmed/35452493
http://dx.doi.org/10.1371/journal.ppat.1010452

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