Cargando…

Development and characterization of rabbit monoclonal antibodies that recognize human spermine oxidase and application to immunohistochemistry of human cancer tissues

The enzyme spermine oxidase (SMOX) is involved in polyamine catabolism and converts spermine to spermidine. The enzymatic reaction generates reactive hydrogen peroxide and aldehydes as by-products that can damage DNA and other biomolecules. Increased expression of SMOX is frequently found in lung, p...

Descripción completa

Detalles Bibliográficos
Autores principales: Tepper, Armand W. J. W., Chu, Gerald, Klaren, Vincent N. A., Kalin, Jay H., Molina-Ortiz, Patricia, Impagliazzo, Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032377/
https://www.ncbi.nlm.nih.gov/pubmed/35452470
http://dx.doi.org/10.1371/journal.pone.0267046