Triazole Modified Tetraiodothyroacetic Acid Conjugated to Polyethylene Glycol, a Thyrointegrin α(v)β(3) Antagonist as a Radio- and Chemo-Sensitizer in Pancreatic Cancer

Thyroid hormone L thyroxine stimulates pancreatic carcinoma cell proliferation via thyrointegrin αvβ3 receptors, and antagonist tetraiodothyroacetic acid (tetrac) inhibits cancer cell growth. Chemically modified bis-triazole-tetrac conjugated with polyethylene glycol (P-bi-TAT) has higher binding af...

Descripción completa

Detalles Bibliográficos
Autores principales: Sudha, Thangirala, Godugu, Kavitha, Glinsky, Gennadi V., Mousa, Shaker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032383/
https://www.ncbi.nlm.nih.gov/pubmed/35453545
http://dx.doi.org/10.3390/biomedicines10040795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032383/
https://www.ncbi.nlm.nih.gov/pubmed/35453545
http://dx.doi.org/10.3390/biomedicines10040795

Ejemplares similares