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Triazole Modified Tetraiodothyroacetic Acid Conjugated to Polyethylene Glycol, a Thyrointegrin α(v)β(3) Antagonist as a Radio- and Chemo-Sensitizer in Pancreatic Cancer

Thyroid hormone L thyroxine stimulates pancreatic carcinoma cell proliferation via thyrointegrin αvβ3 receptors, and antagonist tetraiodothyroacetic acid (tetrac) inhibits cancer cell growth. Chemically modified bis-triazole-tetrac conjugated with polyethylene glycol (P-bi-TAT) has higher binding af...

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Detalles Bibliográficos
Autores principales:	Sudha, Thangirala, Godugu, Kavitha, Glinsky, Gennadi V., Mousa, Shaker A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032383/ https://www.ncbi.nlm.nih.gov/pubmed/35453545 http://dx.doi.org/10.3390/biomedicines10040795

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