A(2A) Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable?

The A(2A) adenosine receptor (A(2A)AR) is one of the four subtypes activated by nucleoside adenosine, and the molecules able to selectively counteract its action are attractive tools for neurodegenerative disorders. In order to find novel A(2A)AR ligands, two series of compounds based on purine and...

Descripción completa

Detalles Bibliográficos
Autores principales: Spinaci, Andrea, Lambertucci, Catia, Buccioni, Michela, Dal Ben, Diego, Graiff, Claudia, Barbalace, Maria Cristina, Hrelia, Silvana, Angeloni, Cristina, Tayebati, Seyed Khosrow, Ubaldi, Massimo, Masi, Alessio, Klotz, Karl-Norbert, Volpini, Rosaria, Marucci, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032385/
https://www.ncbi.nlm.nih.gov/pubmed/35458588
http://dx.doi.org/10.3390/molecules27082386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032385/
https://www.ncbi.nlm.nih.gov/pubmed/35458588
http://dx.doi.org/10.3390/molecules27082386

Ejemplares similares