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Analysis of R848 as an Adjuvant to Improve Inactivated Influenza Vaccine Immunogenicity in Elderly Nonhuman Primates

Elderly individuals are highly susceptible to developing severe outcomes as a result of influenza A virus (IAV) infection. This can be attributed to alterations that span the aged immune system, which also result in reduced responsiveness to the seasonal inactivated vaccine. Given the rapidly increa...

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Detalles Bibliográficos
Autores principales: Crofts, Kali F., Holbrook, Beth C., D’Agostino, Ralph B., Alexander-Miller, Martha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032612/
https://www.ncbi.nlm.nih.gov/pubmed/35455242
http://dx.doi.org/10.3390/vaccines10040494