Anti-Gr-1 Antibody Provides Short-Term Depletion of MDSC in Lymphodepleted Mice with Active-Specific Melanoma Therapy

Lymphodepletion, reconstitution and active-specific tumor cell vaccination (LRAST) enhances the induction of tumor-specific T cells in a murine melanoma model. Myeloid-derived suppressor cells (MDSC) may counteract the induction of tumor-reactive T cells and their therapeutic efficacy. Thus, the aim...

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Detalles Bibliográficos
Autores principales: Rose, Peter, van den Engel, Natasja K., Kovács, Julia R., Hatz, Rudolf A., Boon, Louis, Winter, Hauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032646/
https://www.ncbi.nlm.nih.gov/pubmed/35455309
http://dx.doi.org/10.3390/vaccines10040560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032646/
https://www.ncbi.nlm.nih.gov/pubmed/35455309
http://dx.doi.org/10.3390/vaccines10040560

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