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Anti-Gr-1 Antibody Provides Short-Term Depletion of MDSC in Lymphodepleted Mice with Active-Specific Melanoma Therapy
Lymphodepletion, reconstitution and active-specific tumor cell vaccination (LRAST) enhances the induction of tumor-specific T cells in a murine melanoma model. Myeloid-derived suppressor cells (MDSC) may counteract the induction of tumor-reactive T cells and their therapeutic efficacy. Thus, the aim...
Autores principales: | Rose, Peter, van den Engel, Natasja K., Kovács, Julia R., Hatz, Rudolf A., Boon, Louis, Winter, Hauke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032646/ https://www.ncbi.nlm.nih.gov/pubmed/35455309 http://dx.doi.org/10.3390/vaccines10040560 |
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