Anti-Staphylococcal Activity of the Auranofin Analogue Bearing Acetylcysteine in Place of the Thiosugar: An Experimental and Theoretical Investigation

Auranofin (AF, hereafter) is an orally administered chrysotherapeutic agent approved for the treatment of rheumatoid arthritis that is being repurposed for various indications including bacterial infections. Its likely mode of action involves the impairment of the TrxR system through the binding of...

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Detalles Bibliográficos
Autores principales: Chiaverini, Lorenzo, Pratesi, Alessandro, Cirri, Damiano, Nardinocchi, Arianna, Tolbatov, Iogann, Marrone, Alessandro, Di Luca, Mariagrazia, Marzo, Tiziano, La Mendola, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032686/
https://www.ncbi.nlm.nih.gov/pubmed/35458776
http://dx.doi.org/10.3390/molecules27082578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032686/
https://www.ncbi.nlm.nih.gov/pubmed/35458776
http://dx.doi.org/10.3390/molecules27082578

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