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Anti-Staphylococcal Activity of the Auranofin Analogue Bearing Acetylcysteine in Place of the Thiosugar: An Experimental and Theoretical Investigation
Auranofin (AF, hereafter) is an orally administered chrysotherapeutic agent approved for the treatment of rheumatoid arthritis that is being repurposed for various indications including bacterial infections. Its likely mode of action involves the impairment of the TrxR system through the binding of...
Autores principales: | Chiaverini, Lorenzo, Pratesi, Alessandro, Cirri, Damiano, Nardinocchi, Arianna, Tolbatov, Iogann, Marrone, Alessandro, Di Luca, Mariagrazia, Marzo, Tiziano, La Mendola, Diego |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032686/ https://www.ncbi.nlm.nih.gov/pubmed/35458776 http://dx.doi.org/10.3390/molecules27082578 |
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