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Membrane-Free Stem Cell Extract Enhances Blood–Brain Barrier Integrity by Suppressing NF-κB-Mediated Activation of NLRP3 Inflammasome in Mice with Ischemic Stroke

Membrane-free stem cell extract (MFSCE) of human adipose tissues possesses various biological activities. However, the effects of MFSCE on blood–brain barrier dysfunction and brain damage are unknown. In this study, we determined the role of MFSCE in an ischemic stroke mouse model. Mice were treated...

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Detalles Bibliográficos
Autores principales: Ryu, Ji Hyeon, Kim, Yeonye, Kim, Min Jae, Park, Jisu, Kim, Ji Won, Park, Hye Sook, Kim, Young Sil, Shin, Hwa Kyoung, Shin, Yong-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032759/
https://www.ncbi.nlm.nih.gov/pubmed/35454994
http://dx.doi.org/10.3390/life12040503