Towards Selective Binding to the GLUT5 Transporter: Synthesis, Molecular Dynamics and In Vitro Evaluation of Novel C-3-Modified 2,5-Anhydro-D-mannitol Analogs

Deregulation and changes in energy metabolism are emergent and important biomarkers of cancer cells. The uptake of hexoses in cancer cells is mediated by a family of facilitative hexose membrane-transporter proteins known as Glucose Transporters (GLUTs). In the clinic, numerous breast cancers do not...

Descripción completa

Detalles Bibliográficos
Autores principales: Rana, Natasha, Aziz, Marwa A., Oraby, Ahmed K., Wuest, Melinda, Dufour, Jennifer, Abouzid, Khaled A. M., Wuest, Frank, West, F. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032776/
https://www.ncbi.nlm.nih.gov/pubmed/35456662
http://dx.doi.org/10.3390/pharmaceutics14040828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032776/
https://www.ncbi.nlm.nih.gov/pubmed/35456662
http://dx.doi.org/10.3390/pharmaceutics14040828

Ejemplares similares