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Towards Selective Binding to the GLUT5 Transporter: Synthesis, Molecular Dynamics and In Vitro Evaluation of Novel C-3-Modified 2,5-Anhydro-D-mannitol Analogs

Deregulation and changes in energy metabolism are emergent and important biomarkers of cancer cells. The uptake of hexoses in cancer cells is mediated by a family of facilitative hexose membrane-transporter proteins known as Glucose Transporters (GLUTs). In the clinic, numerous breast cancers do not...

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Detalles Bibliográficos
Autores principales:	Rana, Natasha, Aziz, Marwa A., Oraby, Ahmed K., Wuest, Melinda, Dufour, Jennifer, Abouzid, Khaled A. M., Wuest, Frank, West, F. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032776/ https://www.ncbi.nlm.nih.gov/pubmed/35456662 http://dx.doi.org/10.3390/pharmaceutics14040828

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