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Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis

Linezolid is an efficacious medication for the treatment of drug-resistant tuberculosis but has been associated with serious safety issues that can result in treatment interruption. The objectives of this study were thus to build a population pharmacokinetic model and to use the developed model to e...

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Detalles Bibliográficos
Autores principales: Mockeliunas, Laurynas, Keutzer, Lina, Sturkenboom, Marieke G. G., Bolhuis, Mathieu S., Hulskotte, Lotte M. G., Akkerman, Onno W., Simonsson, Ulrika S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032906/
https://www.ncbi.nlm.nih.gov/pubmed/35456587
http://dx.doi.org/10.3390/pharmaceutics14040753