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Behavioral Phenotype in Heterozygous DAT Rats: Transgenerational Transmission of Maternal Impact and the Role of Genetic Asset

Dopamine transporter (DAT) is involved in dopamine (DA) reuptake in presynaptic terminals. Deletion of DAT results in a hyperdopaminergic KO-rat phenotype. To conduct our studies in heterozygous DAT rats, several pedigree lines were created, with known derivation of the allele (i.e., maternal or pat...

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Detalles Bibliográficos
Autores principales: Manoni, Greta, Puzzo, Concetto, Gigantesco, Antonella, Adriani, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032929/
https://www.ncbi.nlm.nih.gov/pubmed/35448000
http://dx.doi.org/10.3390/brainsci12040469