The Impact of Genetic Polymorphisms in Glutamate-Cysteine Ligase, a Key Enzyme of Glutathione Biosynthesis, on Ischemic Stroke Risk and Brain Infarct Size

The purpose of this pilot study was to explore whether polymorphisms in genes encoding the catalytic (GCLC) and modifier (GCLM) subunits of glutamate-cysteine ligase, a rate-limiting enzyme in glutathione synthesis, play a role in the development of ischemic stroke (IS) and the extent of brain damag...

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Detalles Bibliográficos
Autores principales: Polonikov, Alexey, Bocharova, Iuliia, Azarova, Iuliia, Klyosova, Elena, Bykanova, Marina, Bushueva, Olga, Polonikova, Anna, Churnosov, Mikhail, Solodilova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032935/
https://www.ncbi.nlm.nih.gov/pubmed/35455093
http://dx.doi.org/10.3390/life12040602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032935/
https://www.ncbi.nlm.nih.gov/pubmed/35455093
http://dx.doi.org/10.3390/life12040602

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