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Differential Genetic and Epigenetic Effects of the KLF14 Gene on Body Shape Indices and Metabolic Traits

The KLF14 gene is a key metabolic transcriptional transregulator with monoallelic maternal expression. KLF14 variants are only associated with adipose tissue gene expression, and KLF14 promoter methylation is strongly associated with age. This study investigated whether age, sex, and obesity mediate...

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Detalles Bibliográficos
Autores principales: Wu, Semon, Hsu, Lung-An, Teng, Ming-Sheng, Chou, Hsin-Hua, Ko, Yu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032945/
https://www.ncbi.nlm.nih.gov/pubmed/35456983
http://dx.doi.org/10.3390/ijms23084165