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Cytotoxic Alkylynols of the Sponge Cribrochalina vasculum: Structure, Synthetic Analogs and SAR Studies

A series of twenty-three linear and branched chain mono acetylene lipids were isolated from the Caribbean Sea sponge Cribrochalina vasculum. Seventeen of the compounds, 1–17, are new, while six, 18–23, were previously characterized from the same sponge. Some of the new acetylene-3-hydroxy alkanes 1,...

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Detalles Bibliográficos
Autores principales: Kovalerchik, Dimitry, Zovko, Ana, Hååg, Petra, Sierakowiak, Adam, Viktorsson, Kristina, Lewensohn, Rolf, Ilan, Micha, Carmeli, Shmuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032987/
https://www.ncbi.nlm.nih.gov/pubmed/35447938
http://dx.doi.org/10.3390/md20040265