Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells

Multiple myeloma (MM) and primary effusion lymphoma (PEL) are aggressive hematological cancers, for which the search for new and more effective therapies is needed. Both cancers overexpress c-Myc and are highly dependent on this proto-oncogene for their survival. Although c-Myc inhibition has been s...

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Detalles Bibliográficos
Autores principales: Arena, Andrea, Romeo, Maria Anele, Benedetti, Rossella, Gilardini Montani, Maria Saveria, Cirone, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033049/
https://www.ncbi.nlm.nih.gov/pubmed/35453482
http://dx.doi.org/10.3390/biomedicines10040731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033049/
https://www.ncbi.nlm.nih.gov/pubmed/35453482
http://dx.doi.org/10.3390/biomedicines10040731

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