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EGFR Amplification Is a Phenomenon of IDH Wildtype and TERT Mutated High-Grade Glioma: An Integrated Analysis Using Fluorescence In Situ Hybridization and DNA Methylome Profiling

Gliomas are the most common intrinsic brain tumors in adults, and in accordance with their clinical behavior and patients’ outcome, they are graded by the World Health Organization (WHO) classification of brain tumors. One very interesting candidate for targeted tumor therapy may be epidermal growth...

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Detalles Bibliográficos
Autores principales: Hölzl, Dorothee, Hutarew, Georg, Zellinger, Barbara, Alinger-Scharinger, Beate, Schlicker, Hans U., Schwartz, Christoph, Sotlar, Karl, Kraus, Theo F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033057/
https://www.ncbi.nlm.nih.gov/pubmed/35453544
http://dx.doi.org/10.3390/biomedicines10040794