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SMYD2 Inhibition Downregulates TMPRSS2 and Decreases SARS-CoV-2 Infection in Human Intestinal and Airway Epithelial Cells

The COVID-19 pandemic caused by SARS-CoV-2 has lasted for more than two years. Despite the presence of very effective vaccines, the number of virus variants that escape neutralizing antibodies is growing. Thus, there is still a need for effective antiviral treatments that target virus replication in...

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Detalles Bibliográficos
Autores principales: Yu, Yu-Qiang, Herrmann, Alexandra, Thonn, Veronika, Cordsmeier, Arne, Neurath, Markus F., Ensser, Armin, Becker, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033063/
https://www.ncbi.nlm.nih.gov/pubmed/35455942
http://dx.doi.org/10.3390/cells11081262