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Protein-Based Delivery Systems for Anticancer Metallodrugs: Structure and Biological Activity of the Oxaliplatin/β-Lactoglobulin Adduct

β-lactoglobulin is the major component of whey. Here, the adduct formed upon the reaction of the protein with oxaliplatin (OXA) has been prepared, structurally characterized by X-ray crystallography and electrospray ionization–mass spectrometry, and evaluated as a cytotoxic agent. The data demonstra...

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Detalles Bibliográficos
Autores principales: Monti, Daria Maria, Loreto, Domenico, Iacobucci, Ilaria, Ferraro, Giarita, Pratesi, Alessandro, D’Elia, Luigi, Monti, Maria, Merlino, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033069/
https://www.ncbi.nlm.nih.gov/pubmed/35455422
http://dx.doi.org/10.3390/ph15040425