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Protein-Based Delivery Systems for Anticancer Metallodrugs: Structure and Biological Activity of the Oxaliplatin/β-Lactoglobulin Adduct
β-lactoglobulin is the major component of whey. Here, the adduct formed upon the reaction of the protein with oxaliplatin (OXA) has been prepared, structurally characterized by X-ray crystallography and electrospray ionization–mass spectrometry, and evaluated as a cytotoxic agent. The data demonstra...
Autores principales: | Monti, Daria Maria, Loreto, Domenico, Iacobucci, Ilaria, Ferraro, Giarita, Pratesi, Alessandro, D’Elia, Luigi, Monti, Maria, Merlino, Antonello |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033069/ https://www.ncbi.nlm.nih.gov/pubmed/35455422 http://dx.doi.org/10.3390/ph15040425 |
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