Selecting a stable solid form of remdesivir using microcrystal electron diffraction and crystal structure prediction

Therapeutic options in response to the coronavirus disease 2019 (COVID-19) outbreak are urgently needed. In this communication, we demonstrate how to support selection of a stable solid form of an antiviral drug remdesivir in quick time using the microcrystal electron diffraction (MicroED) technique...

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Detalles Bibliográficos
Autores principales: Sekharan, Sivakumar, Liu, Xuetao, Yang, Zhuocen, Liu, Xiang, Deng, Li, Ruan, Shigang, Abramov, Yuriy, Sun, GuangXu, Li, Sizhu, Zhou, Tian, Shi, Baime, Zeng, Qun, Zeng, Qiao, Chang, Chao, Jin, Yingdi, Shi, Xuekun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033196/
https://www.ncbi.nlm.nih.gov/pubmed/35479679
http://dx.doi.org/10.1039/d1ra03100g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033196/
https://www.ncbi.nlm.nih.gov/pubmed/35479679
http://dx.doi.org/10.1039/d1ra03100g

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