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Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice

AIMS: We have shown that growth hormone (GH) treatment poststroke increases neuroplasticity in peri-infarct areas and the hippocampus, improving motor and cognitive outcomes. We aimed to explore the mechanisms of GH treatment by investigating how GH modulates pathways known to induce neuroplasticity...

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Detalles Bibliográficos
Autores principales: Sanchez-Bezanilla, Sonia, Beard, Daniel J., Hood, Rebecca J., Åberg, N. David, Crock, Patricia, Walker, Frederick R., Nilsson, Michael, Isgaard, Jörgen, Ong, Lin Kooi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033347/
https://www.ncbi.nlm.nih.gov/pubmed/35465399
http://dx.doi.org/10.1155/2022/9983042