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Enzymatic dephosphorylation-triggered self-assembly of DNA amphiphiles

In this work, phosphorylated lipid-conjugated oligonucleotide (DNA-lipid-P) has been synthesized to develop an enzyme-responsive self-assembly of DNA amphiphiles based on dephosphorylation-induced increase of hydrophobicity. Since elevated ALP level is a critical index in some diseases, ALP-triggere...

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Detalles Bibliográficos
Autores principales: Zou, Jianmei, Gao, Qian, Nie, Jinfang, Zhang, Yun, Jin, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033439/
https://www.ncbi.nlm.nih.gov/pubmed/35480953
http://dx.doi.org/10.1039/d1ra01668g