Visible-light enabled room-temperature dealkylative imidation of secondary and tertiary amines promoted by aerobic ruthenium catalysis

Employing sulfonyl azide as a nitrogen donor, a visible-light-enabled aerobic dealkylative imidation of tertiary and secondary amines involving C(sp(3))–C(sp(3)) bond cleavage with moderate to excellent yields at room temperature is described. It has been demonstrated that this imidation could take...

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Detalles Bibliográficos
Autores principales: Yang, Dong, Shi, Jingqi, Chen, Jiaming, Jia, Xiaoqi, Shi, Cuiying, Ma, Lifang, Li, Ziyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033495/
https://www.ncbi.nlm.nih.gov/pubmed/35478631
http://dx.doi.org/10.1039/d0ra10517a
Descripción
Sumario:Employing sulfonyl azide as a nitrogen donor, a visible-light-enabled aerobic dealkylative imidation of tertiary and secondary amines involving C(sp(3))–C(sp(3)) bond cleavage with moderate to excellent yields at room temperature is described. It has been demonstrated that this imidation could take place spontaneously upon visible-light irradiation, and could be facilitated considerably by a ruthenium photocatalyst and oxygen. An alternative mechanism to the previous aerobic photoredox pathway has also been proposed.

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