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Aggresome assembly at the centrosome is driven by CP110–CEP97–CEP290 and centriolar satellites
Protein degradation is critical to maintaining cellular homeostasis, and perturbation of the ubiquitin proteasome system leads to the accumulation of protein aggregates. These aggregates are either directed towards autophagy for destruction or sequestered into an inclusion, termed the aggresome, at...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033585/ https://www.ncbi.nlm.nih.gov/pubmed/35411088 http://dx.doi.org/10.1038/s41556-022-00869-0 |