Cargando…

Aggresome assembly at the centrosome is driven by CP110–CEP97–CEP290 and centriolar satellites

Protein degradation is critical to maintaining cellular homeostasis, and perturbation of the ubiquitin proteasome system leads to the accumulation of protein aggregates. These aggregates are either directed towards autophagy for destruction or sequestered into an inclusion, termed the aggresome, at...

Descripción completa

Detalles Bibliográficos
Autores principales: Prosser, Suzanna L., Tkach, Johnny, Gheiratmand, Ladan, Kim, Jaeyoun, Raught, Brian, Morrison, Ciaran G., Pelletier, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033585/
https://www.ncbi.nlm.nih.gov/pubmed/35411088
http://dx.doi.org/10.1038/s41556-022-00869-0