First total synthesis of chromanone A, preparation of related compounds and evaluation of their antifungal activity against Candida albicans, a biofilm forming agent

A straightforward and convenient approach for the first total syntheses of chromanone A and a related 7-OMe substituted natural product is reported. These unique C-3 substituted 2-hydroxymethyl chromones were recently isolated as fungal metabolites. Chromanone A was synthesized in 25.3% overall yiel...

Descripción completa

Detalles Bibliográficos
Autores principales: Cortés, Iván, Cordisco, Estefanía, Kaufman, Teodoro S., Sortino, Maximiliano A., Svetaz, Laura A., Bracca, Andrea B. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033609/
https://www.ncbi.nlm.nih.gov/pubmed/35479228
http://dx.doi.org/10.1039/d1ra02553h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033609/
https://www.ncbi.nlm.nih.gov/pubmed/35479228
http://dx.doi.org/10.1039/d1ra02553h

Ejemplares similares