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Unique indolizidine alkaloid securinine is a promising scaffold for the development of neuroprotective and antitumor drugs

Alkaloids, secondary plant metabolites, are used in traditional medicine in many countries to treat various pathological conditions. Securinine, a unique indolizidine alkaloid combining four cycles, “6-azobicyclo[3.2.1]octane” as a key structure fused with α,β-unsaturated-γ-lactone and piperidine ri...

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Detalles Bibliográficos
Autores principales: Klochkov, Sergey, Neganova, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033663/
https://www.ncbi.nlm.nih.gov/pubmed/35478659
http://dx.doi.org/10.1039/d1ra02558a