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Copper-catalyzed thioketalization of enones featuring trifluoromethyl groups

Synthetic methods for the preparation of thioketals featuring CF(3) groups are rare. Here, we have developed a copper-catalyzed thioketalization of enones bearing CF(3) groups and various mercaptans. 24 thioketal molecules have been obtained with moderate to excellent yield. Meanwhile, a preparative...

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Detalles Bibliográficos
Autores principales: Zhang, Tongfei, Gao, Zhenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033665/
https://www.ncbi.nlm.nih.gov/pubmed/35479255
http://dx.doi.org/10.1039/d1ra03222d