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Natural steroid-based cationic copolymers cholesterol/diosgenin-r-PDMAEMAs and their pDNA nanoplexes: impact of steroid structures and hydrophobic/hydrophilic ratios on pDNA delivery

Using natural-based lipids to construct biocompatible, controllable and efficient nanocarriers and elucidating their structure–function relationships, was regarded as an important area for creating sustainable biomaterials. Herein, we utilized two natural steroids: cholesterol and diosgenin (bearing...

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Detalles Bibliográficos
Autores principales: Wang, Zhao, Sun, Jingjing, Li, Mingrui, Luo, Ting, Shen, Yulin, Cao, Amin, Sheng, Ruilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033666/
https://www.ncbi.nlm.nih.gov/pubmed/35479247
http://dx.doi.org/10.1039/d1ra00223f