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An adjuvanted zoster vaccine elicits potent cellular immune responses in mice without QS21

Herpes zoster (HZ) is caused by reactivation of latent varicella-zoster virus (VZV) when VZV-specific cellular immunity is insufficient to control reactivation. Currently, Shingrix, which contains the VZV gE protein and GSK’s AS01(B) adjuvant composed of liposomes formulated with cholesterol, monoph...

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Detalles Bibliográficos
Autores principales: Nam, Hyo Jung, Hong, Sung Jun, Lee, Ara, Kim, Jiyeon, Lee, Sangho, Casper, Corey, Carter, Darrick, Reed, Steven G., Simeon, George, Shin, Eui-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033770/
https://www.ncbi.nlm.nih.gov/pubmed/35459225
http://dx.doi.org/10.1038/s41541-022-00467-z