A DNA vaccine targeting VEE virus delivered by needle-free jet-injection protects macaques against aerosol challenge

We have previously shown that DNA vaccines expressing codon optimized alphavirus envelope glycoprotein genes protect both mice and nonhuman primates from viral challenge when delivered by particle-mediated epidermal delivery (PMED) or intramuscular (IM) electroporation (EP). Another technology with...

Descripción completa

Detalles Bibliográficos
Autores principales: Suschak, John J., Bixler, Sandra L., Badger, Catherine V., Spik, Kristin W., Kwilas, Steven A., Rossi, Franco D., Twenhafel, Nancy, Adams, Melissa L., Shoemaker, Charles J., Spiegel, Erin, Hooper, Jay W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033795/
https://www.ncbi.nlm.nih.gov/pubmed/35459271
http://dx.doi.org/10.1038/s41541-022-00469-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033795/
https://www.ncbi.nlm.nih.gov/pubmed/35459271
http://dx.doi.org/10.1038/s41541-022-00469-x

Ejemplares similares