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A stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway

Genomic instability plays a key role in the initiation and progression of colorectal cancer (CRC). Although cancer driver genes in CRC have been well characterized, identifying novel genes associated with carcinogenesis and treatment remains challenging because of tumor heterogeneity. Here, we analy...

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Detalles Bibliográficos
Autores principales: Peng, Lin, Zhao, Min, Liu, Tianqi, Chen, Jiangbo, Gao, Pin, Chen, Lei, Xing, Pu, Wang, Zaozao, Di, Jiabo, Xu, Qiang, Qu, Hong, Jiang, Beihai, Su, Xiangqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033806/
https://www.ncbi.nlm.nih.gov/pubmed/35459861
http://dx.doi.org/10.1038/s41419-022-04844-3