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A stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway
Genomic instability plays a key role in the initiation and progression of colorectal cancer (CRC). Although cancer driver genes in CRC have been well characterized, identifying novel genes associated with carcinogenesis and treatment remains challenging because of tumor heterogeneity. Here, we analy...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033806/ https://www.ncbi.nlm.nih.gov/pubmed/35459861 http://dx.doi.org/10.1038/s41419-022-04844-3 |