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p63, a key regulator of Ago2, links to the microRNA-144 cluster

ABSTRACT: As a key component of the RNA-induced silencing complex (RISC), Argonaute2 (Ago2) exhibits a dual function regulatory role in tumor progression. However, the mechanistic basis of differential regulation remains elusive. p63 is a homolog of the tumor suppressor p53. p63 isoforms play a crit...

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Detalles Bibliográficos
Autores principales: Wang, Benfan, Wu, H. Helena, Abuetabh, Yasser, Leng, Sarah, Davidge, Sandra T., Flores, Elsa R., Eisenstat, David D., Leng, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033807/
https://www.ncbi.nlm.nih.gov/pubmed/35459267
http://dx.doi.org/10.1038/s41419-022-04854-1