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p63, a key regulator of Ago2, links to the microRNA-144 cluster
ABSTRACT: As a key component of the RNA-induced silencing complex (RISC), Argonaute2 (Ago2) exhibits a dual function regulatory role in tumor progression. However, the mechanistic basis of differential regulation remains elusive. p63 is a homolog of the tumor suppressor p53. p63 isoforms play a crit...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033807/ https://www.ncbi.nlm.nih.gov/pubmed/35459267 http://dx.doi.org/10.1038/s41419-022-04854-1 |