Cargando…
p63, a key regulator of Ago2, links to the microRNA-144 cluster
ABSTRACT: As a key component of the RNA-induced silencing complex (RISC), Argonaute2 (Ago2) exhibits a dual function regulatory role in tumor progression. However, the mechanistic basis of differential regulation remains elusive. p63 is a homolog of the tumor suppressor p53. p63 isoforms play a crit...
Autores principales: | Wang, Benfan, Wu, H. Helena, Abuetabh, Yasser, Leng, Sarah, Davidge, Sandra T., Flores, Elsa R., Eisenstat, David D., Leng, Roger |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033807/ https://www.ncbi.nlm.nih.gov/pubmed/35459267 http://dx.doi.org/10.1038/s41419-022-04854-1 |
Ejemplares similares
-
Hsp70 acts as a fine-switch that controls E3 ligase CHIP-mediated TAp63 and ΔNp63 ubiquitination and degradation
por: Wu, H Helena, et al.
Publicado: (2021) -
The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System
por: Armstrong, Stephen R., et al.
Publicado: (2016) -
The SWIB/MDM2 motif of UBE4B activates the p53 pathway
por: Wu, H. Helena, et al.
Publicado: (2023) -
Graphene Oxide Nanoparticles Induce Apoptosis in wild-type and CRISPR/Cas9-IGF/IGFBP3 knocked-out Osteosarcoma Cells
por: Burnett, Mervin, et al.
Publicado: (2020) -
DNA damage response revisited: the p53 family and its regulators provide endless cancer therapy opportunities
por: Abuetabh, Yasser, et al.
Publicado: (2022)