Automated quantitative high-throughput multiplex immunofluorescence pipeline to evaluate OXPHOS defects in formalin-fixed human prostate tissue

Advances in multiplex immunofluorescence (mIF) and digital image analysis has enabled simultaneous assessment of protein defects in electron transport chain components. However, current manual methodology is time consuming and labour intensive. Therefore, we developed an automated high-throughput mI...

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Detalles Bibliográficos
Autores principales: Sachdeva, Ashwin, Hart, Claire A., Carey, Christopher D., Vincent, Amy E., Greaves, Laura C., Heer, Rakesh, Oliveira, Pedro, Brown, Michael D., Clarke, Noel W., Turnbull, Doug M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033818/
https://www.ncbi.nlm.nih.gov/pubmed/35459777
http://dx.doi.org/10.1038/s41598-022-10588-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033818/
https://www.ncbi.nlm.nih.gov/pubmed/35459777
http://dx.doi.org/10.1038/s41598-022-10588-z

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