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Numerical learning of deep features from drug-exposed cell images to calculate IC50 without staining

To facilitate rapid determination of cellular viability caused by the inhibitory effect of drugs, numerical deep learning algorithms was used for unlabeled cell culture images captured by a light microscope as input. In this study, A549, HEK293, and NCI-H1975 cells were cultured, each of which have...

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Detalles Bibliográficos
Autores principales: Cho, Kookrae, Choi, Eun-Sook, Kim, Jung-Hee, Son, Jong-Wuk, Kim, Eunjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033873/
https://www.ncbi.nlm.nih.gov/pubmed/35459284
http://dx.doi.org/10.1038/s41598-022-10643-9